3C-DFE is a lesser-known psychedelic drug, which is a fluorinated derivative of 3C-E. It was first synthesised by Daniel Trachsel in 2002, and has been reported as showing similar psychedelic activity to related compounds, with a dose range of around 20–40 mg and a duration of approximately 10 hours.: 736 Despite its reported psychedelic activity, binding studies in vitro showed 3C-DFE to have a surprisingly weak binding affinity of 2695 nM at 5-HT2A with negligible affinity at 5-HT2C,: 737 making it only slightly higher affinity than mescaline, despite its higher potency in vivo.
See also
- 3C (psychedelics)
- 2C-TFE
- Escaline
- DOTFM
- 2C-T-21
- 2C-T-21.5
- 2C-T-28
- 3C-P
- Trifluoromescaline
References
